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Treatment

What to ask your GP to test, which supplements and medications have evidence behind them, and what to avoid, with honest labels on the strength of that evidence.

There’s no approved cure for ME/CFS yet. But some treatments help some people with some symptoms, and some things reliably make it worse. This section sets out the evidence honestly so you and your doctor can decide what’s worth trying.

Tests to ask your GP for

The standard tests to rule out other causes, extra tests worth asking for in ME/CFS, how to read common results, and a script you can take to your appointment.

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Supplements

The energy-metabolism supplements with evidence in ME/CFS (creatine, CoQ10, NADH/NMN, carnitine and others), what the research shows, and how to judge whether they're working.

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Medications

Off-label medications used in ME/CFS (low-dose naltrexone, rapamycin, pyridostigmine, aripiprazole and more) and what the evidence really shows.

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What to avoid

Treatments, tests and habits that can make ME/CFS worse, and how to spot hype.

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